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str.rindex(str, beg=0, end=len(string))

#!/usr/bin/python3
str1 = "this is really a string example....wow!!!"
str2 = "is"

print (str1.rindex(str2))
print (str1.rindex(str2,10))

5
Traceback (most recent call last):
  File "test.py", line 6, in <module>
    print (str1.rindex(str2,10))
ValueError: substring not found