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os.lchflags(path, flags)

#!/usr/bin/python3

import os, sys

# Open file
path = "/var/www/html/foo.txt"
fd = os.open( path, os.O_RDWR|os.O_CREAT )

# Close file
os.close( fd )

# Modify file flags
ret = os.lchflags(path, os.UF_IMMUTABLE )

print ("File flags modified successfully!!")

File flags modified successfully!!