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os.mknod(filename[, mode=0600[, device=0]])

#!/usr/bin/python3

import os
import stat

filename = '/tmp/tmpfile'
mode = 0600|stat.S_IRUSR

# Specify different modes for the filesystem node
os.mknod(filename, mode)

-rw-------. 1 root   root         0 Apr 30 02:38 tmpfile